Wasp: While Wasp is in Giant hero form, how does her second ability interact with the guard keyword?

Wasp’s second ability allows her basic attack to simultaneously damage each enemy that Wasp chooses. Although Wasp may choose the villain as a target while a card with the guard keyword is in play, no damage will be dealt to the villain. Due to the simultaneous nature of this ability, this applies even if the card with the guard keyword is removed from play during her basic attack’s resolution

-Official FAQ (1.4)